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female hsd icr cd 1  (Inotiv)
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Inotiv female hsd icr cd 1
Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
Female Hsd Icr Cd 1, supplied by Inotiv, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/female hsd icr cd 1/product/Inotiv
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female hsd icr cd 1 - by Bioz Stars, 2026-03
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mice female hsd icr cd 1  (Inotiv)
94
Inotiv mice female hsd icr cd 1
Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
Mice Female Hsd Icr Cd 1, supplied by Inotiv, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mice female hsd icr cd 1/product/Inotiv
Average 94 stars, based on 1 article reviews
mice female hsd icr cd 1 - by Bioz Stars, 2026-03
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hsd icr cd 1 mice  (Inotiv)
94
Inotiv hsd icr cd 1 mice
Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
Hsd Icr Cd 1 Mice, supplied by Inotiv, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hsd icr cd 1 mice/product/Inotiv
Average 94 stars, based on 1 article reviews
hsd icr cd 1 mice - by Bioz Stars, 2026-03
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cd-1 icr mouse  (Charles River Laboratories)
90
Charles River Laboratories cd-1 icr mouse
Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
Cd 1 Icr Mouse, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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2% cd-1 (icr) mouse pooled plasma  (BioIVT Inc)
90
BioIVT Inc 2% cd-1 (icr) mouse pooled plasma
Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
2% Cd 1 (Icr) Mouse Pooled Plasma, supplied by BioIVT Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/2% cd-1 (icr) mouse pooled plasma/product/BioIVT Inc
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2% cd-1 (icr) mouse pooled plasma - by Bioz Stars, 2026-03
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cd-1® igs mouse [crl:cd1(icr)]  (Charles River Laboratories)
90
Charles River Laboratories cd-1® igs mouse [crl:cd1(icr)]
Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
Cd 1® Igs Mouse [Crl:Cd1(Icr)], supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cd-1® igs mouse [crl:cd1(icr)]/product/Charles River Laboratories
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cd-1 (icr) mouse serum  (BioIVT Inc)
90
BioIVT Inc cd-1 (icr) mouse serum
Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
Cd 1 (Icr) Mouse Serum, supplied by BioIVT Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cd-1 (icr) mouse serum/product/BioIVT Inc
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cd-1 (icr) mouse serum - by Bioz Stars, 2026-03
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hsd icr cd 1  (Inotiv)
94
Inotiv hsd icr cd 1
Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
Hsd Icr Cd 1, supplied by Inotiv, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hsd icr cd 1/product/Inotiv
Average 94 stars, based on 1 article reviews
hsd icr cd 1 - by Bioz Stars, 2026-03
94/100 stars
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icr (cd-1 ® ) mouse  (S2 Genomics)
90
S2 Genomics icr (cd-1 ® ) mouse
Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived <t>from</t> <t>CD-1</t> mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).
Icr (Cd 1 ® ) Mouse, supplied by S2 Genomics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/icr (cd-1 ® ) mouse/product/S2 Genomics
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icr (cd-1 ® ) mouse - by Bioz Stars, 2026-03
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Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived from CD-1 mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).

Journal: Scientific Reports

Article Title: Aluminum adjuvants differentially induce IL-1β release in vitro yet share NLRP3 inflammasome-independent adjuvant effects in vivo

doi: 10.1038/s41598-025-34660-6

Figure Lengend Snippet: Dose-dependent inflammasome activation and cytotoxicity in LPS-primed mouse macrophages and dendritic cells stimulated with AH or AP. BMDMs ( a–c ) and BMDCs ( d – f ) derived from CD-1 mice were incubated in medium only (M) or primed with LPS and stimulated with increasing concentrations of AH or AP for 24 h. ( a , d ). Cytotoxicity was assessed by measuring lactate dehydrogenase (LDH) release. ( b , e ) IL-1β secretion was quantified by ELISA. ( c , f ) Western blot analysis for IL-1β of supernatants (Sup) and lysates (Lys). Ten µg of total protein was loaded per lane for BMDMs (c) and 20 µg for BMDCs (f). Bars represent the mean ± SEM of triplicate wells. Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).

Article Snippet: Female Hsd:ICR (CD-1®) (CD-1) mice were purchased from Inotiv (Indianapolis, IN).

Techniques: Activation Assay, Derivative Assay, Incubation, Enzyme-linked Immunosorbent Assay, Western Blot

The antibody response to protein antigens injected with aluminum adjuvants does not require functional NLRP3. ( A , B ) C57BL/6J WT and Nlrp3 -/- mice were injected twice with OVA and AH ( A ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( B ). The graphs show the mean ± SE of four mice per group. ( C , D ) CD-1 mice were treated with MCC950 or untreated and then injected twice with OVA and AH ( C ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( D ). The graphs show data from individual mice and the mean ± SE of 4–5 mice per group. ns – not significant (Student’s t-test, p > 0.05).

Journal: Scientific Reports

Article Title: Aluminum adjuvants differentially induce IL-1β release in vitro yet share NLRP3 inflammasome-independent adjuvant effects in vivo

doi: 10.1038/s41598-025-34660-6

Figure Lengend Snippet: The antibody response to protein antigens injected with aluminum adjuvants does not require functional NLRP3. ( A , B ) C57BL/6J WT and Nlrp3 -/- mice were injected twice with OVA and AH ( A ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( B ). The graphs show the mean ± SE of four mice per group. ( C , D ) CD-1 mice were treated with MCC950 or untreated and then injected twice with OVA and AH ( C ) or nucleoprotein of SARS-CoV-2 (NP) and AP ( D ). The graphs show data from individual mice and the mean ± SE of 4–5 mice per group. ns – not significant (Student’s t-test, p > 0.05).

Article Snippet: Female Hsd:ICR (CD-1®) (CD-1) mice were purchased from Inotiv (Indianapolis, IN).

Techniques: Injection, Functional Assay